Course syllabus

Lecture courses: Available to current Oxford students only.

Year 2 (2020-21)

• Developmental Biology I
• Introduction to Immunology
• Macromolecule Targetting and Transport
• Intracellular Signalling: Principles and Applications

Year 3 (2021-22)

• Apoptosis
• Cell Growth and Division
• Cell Matrix
• Developmental Biology II
• Molecular and Cellular Immunology
• Systems Biology of the Cell Cycle

Revision

Revision TT22

Course Leader:

Professor P. Ligoxygakis
New Biochemistry
Telephone: 13266

Summary:

This part of the course takes knowledge of macromolecular structure, metabolic biochemistry and bioenergetics, gene expression and gene control, and integrates these approaches into the analysis and understanding of complex biological phenomena such as animal development, immunity and neuronal function. The course consists of approximately 30 lectures (second year), 50 lectures (third year), associated practicals and problem-solving sessions. All students are encouraged to attend relevant Departmental Colloquia and seminars. Third years students in particular should regard the Departmental Colloquia on Mondays as an integral part of their course. The course coordinator is Professor Petros Ligoxygakis. You should contact him if you have problems or suggestions for change. Please take the time to fill out the course questionnaires, so that we can respond to your constructive suggestions and improve the course.

The aims of this course are:

The second year part of the course aims to introduce you to:

• The basic principles of cell biology – how macromolecules are moved around the cell and across membranes, and how they are organized into macromolecular assemblages
• The properties and synthesis of lipid membranes
• The fundamentals of developmental biology: methods used for investigating development, in particular genetics; involvement of diverse intercellular signalling systems; molecular basis of sex determination, establishment of major embryonic axes, developmental induction and signal transduction

By the end of this course you should understand:

• Basic principles of macromolecular trafficking in cells
• Organisation and synthesis of membranes
• Basic principles of developmental biology and developmental genetics

References:

Detailed references are provided with each lecture handout/powerpoint. Textbook material can be found in:

• Alberts B et al. Molecular biology of the cell (Fifth Edition)
• Gilbert S Developmental biology (Eighth Edition)